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Major depression affects 10-15% of women, men, and kids in the United States each year. About 10-30% of them don’t get relief from traditional antidepressant therapy.  Although ketamine and antidepressants each target brain chemicals that regulate mood, that's where their similarities end. Ketamine works differently from the way antidepressants do....

Is Spravato More Effective than Ketamine? To much fanfare, Johnson & Johnson’s drug company, Janssen Pharmaceuticals Inc., has been testing a new drug for treatment-resistant depression, Spravato – also known as esketamine. Chemically, the generic ketamine and Jonson & Johnson’s patented Spravato are very similar. Spravato will undoubtedly be much...

Esketamine Does Not Live Up to Hopes for a More Convenient Ketamine Eskatmine (brand name Spravato) is a new nasal spray that works like ketamine. To treat depression, ketamine has been delivered through an IV or breathed in as a nebulizer treatment. The idea of a nasal spray has been...

How Much Does Spravato Cost? Spravato (generic name esketamine) is the newly patented and newly FDA approved modification of ketamine. It’s been released by Johnson & Johnson’s Janssen Pharmaceuticals, Inc. with much fanfare. They claim it’s a new kind of drug for treatment-resistant depression. Unfortunately, it’s hard to find any...

Is Spravato Nasal Spray for Depression Really New? In March 2019, the FDA approved Johnson & Johnson’s new depression drug. Company spokespeople have said it uses the “first new mechanism of action in decades.” That means it should work on the body in a new way. But wait . ....